PRP / PRFM Facial Rejuvenation in Medford, Oregon

Medically reviewed by Alexander Bonato, MD — October 2026

Freckled woman resting her face in her hands

Regenerate. Brighten. Restore Your Natural Glow.

At Bonato MD Aesthetics in Medford, Oregon, Alexander Bonato, MD, personally performs PRP and PRFM facial treatments using preparations made from your own blood.

Dr. Bonato uses the Cellenis PRP system. When preparing PRFM, he activates the PRP with calcium chloride to begin fibrin-matrix formation. Treatment is selected following an assessment of your skin, medical history, and goals.

These treatments aim to improve skin quality gradually. The amount of improvement varies, and a consultation helps determine whether PRP, PRFM, or another approach best fits your concerns.

Every treatment at Bonato MD Aesthetics is performed by Dr. Alex Bonato, MD — board-certified in Internal Medicine by the American Board of Internal Medicine. You'll always be treated by Dr. Bonato himself, from consultation through treatment. Serving Medford and Southern Oregon. Meet Dr. Bonato →

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Gloved hand holding three small syringes

What Are PRP and PRFM?

Platelet-rich plasma (PRP) is prepared by drawing a small blood sample and processing it to concentrate platelets within the plasma. Platelets contain growth factors involved in tissue repair.

At Bonato MD Aesthetics, PRP is prepared using Cellenis. For platelet-rich fibrin matrix (PRFM), Dr. Bonato adds calcium chloride, initiating the process that forms a fibrin network.

PRP and activated PRP differ in preparation and handling. A fibrin matrix does not automatically mean a better result or a longer-lasting outcome. Dr. Bonato selects the preparation and treatment approach for your individual circumstances.

Common treatment areas
PRP and PRFM can be used to treat a variety of facial concerns, including:

Under-Eye Area

Full Face Rejuvenation

Cheeks & Temples

Smile Lines & Marionette Lines

Forehead & Brow Area

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Each treatment is fully personalized, allowing Dr. Bonato to address your unique areas of concern for a naturally revitalized appearance.

How Much Does PRP Cost in Medford?

PRP injections start at $450. PRP applied topically during microneedling is priced with that treatment at $550.

PRP uses growth factors concentrated from your own blood, so there is no product to price by the syringe — what you are paying for is the draw, the processing, and physician-performed placement. Your free consultation determines which approach fits what you are treating and how many sessions to plan for. Results build gradually over a series rather than appearing immediately.

PRP injections from $450 · With microneedling: $550 · Free consultation

Woman with eyes closed touching her neck and jawline

Potential Benefits of PRP / PRFM.

May improve selected aspects of skin quality, including texture and elasticity
May soften the appearance of fine lines
Uses a platelet preparation derived from your own blood
Offers an option for patients whose goals and medical history make treatment appropriate

Evidence for facial rejuvenation is developing, and results differ between patients and preparation methods. PRP and PRFM do not reliably correct every cause of dark circles, hollowing, or facial aging.

It can be used in conjunction with microneedling to help rejuvenate skin.

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"I’ve seen Dr. Bonato multiple times now for laser (Nouvaderm), Derma PRP, and neurotoxin treatments, and I couldn’t be happier with my results. My skin looks and feels incredible — I’ve genuinely never received so many compliments about how “glowy” and refreshed my complexion is."

Bonnie S.
"I went for microneedling and PRP with Dr. Bonato. It was such a good experience. The clinic was cute and very clean. He makes excellent recommendations based off of medical expertise. I’ve gotten a million compliments on my skin. Just do it, just book."

Hannah M.

PRP / PRFM

Pair With Complementary Treatments

Other treatments may address different concerns. Dr. Bonato can discuss whether combining treatments is appropriate and how to schedule them.

Wrinkle Relaxers

Complements your rejuvenation with subtle wrinkle softening.

Explore Dysport
Sculptra

Rebuilds structural volume and firmness beneath the skin.

Explore Sculptra
Microneedling with PRP

Explore physician-performed microneedling and optional topical PRP.

Explore Microneedling
VI Peel

Refines tone and smooths surface imperfections.

Explore VI Peel

QUESTIONS? WE HAVE ANSWERS!

FAQs

Both begin with a platelet-rich preparation from your own blood. At this practice, Dr. Bonato prepares Cellenis PRP and adds calcium chloride when preparing PRFM, initiating fibrin-matrix formation. The preparation and handling differ; PRFM is not automatically more effective or longer-lasting.
Any improvement develops gradually over the weeks and months after treatment. The timing and degree of response vary. Early swelling can temporarily change the appearance of a treated area and should not be mistaken for the final result.
Dr. Bonato may recommend a series, with the number and spacing of sessions selected following your assessment.
It may be appropriate for selected patients, but an assessment is essential. Dark circles, fine lines, puffiness, and hollowing can have different causes, and PRP or PRFM may not address the main cause of your concern.
Using your own blood does not eliminate treatment risks. Dr. Bonato will discuss expected benefits, limitations, alternatives, and the risks of injections in this area.
There is no single duration that applies to everyone. Results depend on the concern treated, preparation method, treatment course, and individual response. Dr. Bonato will review your progress before recommending further treatment or maintenance.
Bruising, swelling, redness, tenderness, and temporary unevenness can occur after facial injections. Their severity and duration vary, and visible bruising or swelling may last beyond the first 48 hours.
Follow your written instructions about skin care, makeup, exercise, and follow-up. Contact the practice if symptoms are worsening or concerning.
Blood collection and injections can cause pain, bruising, swelling, bleeding, and infection. Facial injections also carry a risk of vascular injury. Serious complications, including skin injury and vision loss, have been reported after facial PRP injections.
Seek immediate medical attention for vision changes, stroke symptoms, severe unusual pain, or concerning skin discoloration after treatment.
No. The PRFM preparation described here and Cellenis Derma PRP gel filler involve different preparation methods and treatment goals. Dr. Bonato can explain which approach, if any, fits your concerns.